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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5095f972c19beda58776976a2603342c480f91c7940492583e8d0a41eb6e42c7' 
  AND token = 'N5ixQDcLToZWPLELqsbyzf/HIWX5lklyMcAl8531jm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}