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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46892c856900c6063a7fd95756b07103a0825f436c2544b2b61820b0a21cccba' 
  AND token = 'U/NiYaDWgneMQI8ypzweLa8tSLvUhTeeRtvW7TDRFKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}