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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3cc8b4503a34b8cfbdf51dafe422c75aa5de44a58ac56c215145414b4f19049d' 
  AND token = 'bwh+v94N4gbw+qXpD07oKy8wHZvWbQSAqH9xrOjzgp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}