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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c4296daedb6bef598ab4cb3e21959c6a550abd6445ff52880cac660330fc2fc2' 
  AND token = 'Bmd73g3d3RPD4FSnAF7FQmfMtT76JTpQTkdvZqVVtJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}