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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1773189b45e2395ad61cff1998680ed0525b0af28107aa1e526e36f8fb7a00e4' 
  AND token = 'ffa/JAsQ8+24I9flxOm83kOO8RyVYSsrlJQrwFMac0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}