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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65cfb2dffcc58b0d3abef028241b36039b2b9b32428e29e4467bba0e40d3e77b' 
  AND token = 'YCDKaKBZU5mLkwG1LR4cTvZbn2LRvdcXrbnI4Whnx04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}