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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ed18340a58c549a3b2b6586cd61acac09de44716915be930efda75839cf0829' 
  AND token = '2Ncq+b3FocPm24TVFHJZQqmC0MlbMyYOdKEahGAriro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}