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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'de6ad3a62ea9ce488105fc15dc64f4dc7449766ce241666f1550408c5901958c' 
  AND token = '2DTi1tkFnAJIJoWwVesf3+PAAN30o3uAxkxLZYwurXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}