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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e73e3481a93f0727b81a13c21e15185535660681c366f90bff5dc33361286ef' 
  AND token = 'usiU0DfWN2rpTy/HJdlV3/S3zrfuSXCxxfVNt6MZTOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}