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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '758e561bd5a817221ebd25745889c07630550b6bf7b1b3f2e05082e6f60c2ead' 
  AND token = 'WdWgSkCb365B6YmXLfV6/BbWsRqIGy9z1igNen5R46s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}