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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0dfa6a22a1ed35f88d39d0d655f8925a50003c8d6554a9cb260aaf0acef770a2' 
  AND token = 'GADSmgocq5WWue5RV7wl9JK5rRKVTwW+uPfvU6pVXm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}