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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4b6682224c94d0d3b29565172da0f796d5e51e621dca9a956c47479649ed7f6' 
  AND token = 'PxOu8Tj89HZmMDodMLA5zGT+H6vmHXiXOuHH6XCfBs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}