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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b057a4e050d8ec3aaee213140ac51742bf053001501afa1effec440138b9db4f' 
  AND token = 'tnLSszN8lLvTF9UUsBlk3O7sCQ0TqrwucHTjJgnBTm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}