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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '434fe4cab4ec29e81d5a0754cb03347bd26df539c61059b05a01e7866e0d3974' 
  AND token = 'bozO2W7dQo9O9liMFkc3yJVEtvGUDOvnzeml3QDZ1Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}