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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e219f17d5797e762bfea868aa2518c185823bc8ce481c1409aba4ce0b0e8e4e4' 
  AND token = 'b81c9rmlt8h1qmXkjWLz/qPEuQXTXCcdwTuVGkeoxKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}