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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a1e4fc6fe81089d2c7018b26118897dcf1fa90e98e6538c4eae74491affdcd1' 
  AND token = 'TC2NuE2rqwDTufhDhRA24gD8YVBmdY3PMot1ZI4qbdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}