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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c4c30e61ea3509e444716be32c910ea0695da6005bf3c304fd8af54e7d80db2' 
  AND token = 'u+9QkvDqD0dJwHfdM+A2dWWgEckj/YiFb2b5Z1TkJMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}