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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '380f270052ff4a6002e666e2127de1b55f56678c4ff6f23d2c22d8d9ad8affb1' 
  AND token = 'qhupKPlq32dnc6X8Epjyhgg98pUVjs4uyRLdWxNbAfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}