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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16f41f462c99081aea48e6c7646ee1338964c07c6be9c5ae2aed66d38d7e0f00' 
  AND token = 'R8WUC/WIzUFWdYVeoT//qUgW0F017o/ciIsPy53dxSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}