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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c27f335ca458def74cf0fb1e17a072386ef673dd3fcffbbba0444ac5e22064a1' 
  AND token = 'vow6aOLLmobEQ5KlIixA9rSM/WvXz2Gi04EdcnOd8YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}