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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c3565d8f2d9061b8c92855d5fee08c25c23e5782b8ff8489ec0beb7344f8e991' 
  AND token = 'ezdwU9JCeGzX39mGMeO3iZ21S7RcUtR2PWdh1t9VHRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}