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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '650f0d08de4e4629010f8ad71d75e032ee7bedf6869befd2d528d8cdd5d0fdce' 
  AND token = '1A2hmQUEEdM+o9OdbBIj+D5/KsqbNlCkvf4x6NRq1ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}