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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a564c25cdbe51c2e49355ce9fbfa6675c99d0048769729533426fde0f71ca04f' 
  AND token = 'k+aJUqWz5LxVHcptsbwH1gy1kROJH+2JxGo3AIlDrmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}