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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '127bc07c7bf6a75a9a583bf53b23e3b44a000700b13f1b74a8093c9200b15308' 
  AND token = 'YzZOT4iZuoLHtMvsD64QNL/2W0qCC0b1S7euZZGE3q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}