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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5e4bb5a4f1e9c26987ad27eccffcca263a39f83a18f6ce7bf3117e2873380ad' 
  AND token = '5GX8kAJ7UlGLx3tLwcQLWDg0/TwhzDw6PNYvwltO35A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}