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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed0f5cdc333158e3bdc43ecb080b5ea942d83396f06f08cce355e3c7af0353b6' 
  AND token = 'AllP5O0NZcj8xdBAS9Vc5s0xMQ6nnbudZZT5HAXPbHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}