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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e432f9e5fb9719bac5c3093bf090469dfe8f0bda42a025de7fe10090e8bc062' 
  AND token = 'i0/yEEwlQveE6fG1EvUhCpI6sizAA/oL+RePOMfmToA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}