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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9117e3eff234f676fa23599e53cf6b69c64c698dfed37d0986a0195b9908d1d8' 
  AND token = 'M5Xw2+4T+QAvjmBTQETt3XOtR6ldzw0V1fcDsazCsiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}