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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22146112d3934adbd70cb09d174aa514e1a41cea9d08383f552f20ea6ee394e6' 
  AND token = '/ucR9ymmwExF9U/W9PPllhnc56GA/N49FCwn35lELM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}