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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a80109930f24df335ba7dd70b708dfa41baff2bc601198da7b02f139727770b' 
  AND token = 'PWhnXCM52WqyQjGU22FsDYgnb3ziWJgur447jpTfkHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}