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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a48d9152867f73cb98ad0c90271fc11461b47488e3f3ce9ed33e512052796014' 
  AND token = 'mjbk+2Ks+v0dRzibOTz+fMg4/uA1zCmRwM1Ps1D96yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}