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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c7d9a489af4a4b1ac7e77cec380a1d28f81d0c8c011a4a59e0b7b6184434c265' 
  AND token = 'U86/csgETDdspt+9aDnZqb0qb4DcQS1qAx9kZ3fIWP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}