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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '979f01826878cc82c9f5478e77de0fc623a63f3c9e2c2240fb1b9c65afe16289' 
  AND token = 'VgNUPM8HIEa3Ua7iIDBowpZcNjCgSTppbHqHmhUcmnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}