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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '827024d6c8fce94220907ad7e67120446687f1cd234555662f87baa4dbdf0da7' 
  AND token = 'SAo4oIBI2GZkBQaz1Dqii/aiqS45dyQk4VTAkSbWm7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}