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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f6a1d2a32157e4916f35c228ddc4b2e8e622f1037c5667f2ee9e483c369e22d' 
  AND token = '5oohjTNTbEE3irCBg3Fz4aYcimkIzU/CvcLdeMl0Y+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}