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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8748a76f1a03c8b38b05767b4f491cb255bf9d561d25c0f3b77850c8a152c845' 
  AND token = '00XuraCUjgHYNHHANen/ts+lUp7bCG6S7Ee0Jxky1KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}