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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0592640d924b2794fdacad1533b6afd59b598287bd0a205ac7cf8aae73149b8a' 
  AND token = 'YWDo2dOOnfYOAmxfur+lI+KikAVRaFREiV5xTAqmQpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}