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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e99c97e49cb426c83b85c0caa972e0800fe8d43a4a2432005e95d4f6a9cac6ac' 
  AND token = 'UpTlsxF+WYEC0dfICP1SWMYap4MruC/rNBkWDQWUrh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}