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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49dbc373780aafde9bf746c88360080e5cac6972818928876dcf7c1f0bef50f0' 
  AND token = 'seSz8xdROhiJDV7LfxJqyPLDnsU1Wrr0uhwqCcSH9nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}