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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f2d4e0f09f0bd4c63e27f2a42ad4a8815c65c0a72834b6d78556f1f548634b37' 
  AND token = 'P+diEYwizLEzXflqtLtWZa5a2LWrbp3IR21lVOKEmQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}