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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d2f1ec0c41e27db1ffb133c0496d09a9d2901141a024d9342264324d989e60e' 
  AND token = 'd3lnLWYj8XC05GVSgGpSRrUiQys48nnDxiBKvZCIvfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}