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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '29dad3adbbedcfe7628b3ca9e5cef44dc6087f10ee45c4be8cc5768f63ada22b' 
  AND token = 'JfR6Mx/dIRGn2UGkEqkDgNpPilqU3vyfOb7ANCuhfq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}