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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dea43d4d91d7dfd833e42461ae8d7879c5024377668d5e532596260b0adcc7a1' 
  AND token = 'IlVjNRFKjmuoPXyWa54K9iExwNZxIygpKcmp3mnA36I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}