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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '28ee8ae4cb37c4b41c04b9022c098f476f02d5b23e628dee4133ef766b1d1050' 
  AND token = 'WPdu40RrwX1r6s3oS8d5W420AFTGazp7JkUR0jPaUGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}