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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35649812c133f16c3f3ef6626dbeeaf61fe859eb49d23cf352ac1b7723cfaa97' 
  AND token = 'da+fsN2XN1euX2YQ9/BOBy4uwieCvqhqrHDKNbWS0fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}