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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05029aa0380c79c7e742c1015b552d39b493812bacd65bc54be2ca57d2fd8c22' 
  AND token = '6Sl1Vy3QhwyGlzW90jl98kOk2i/meC5TH8yGQQN557Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}