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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5105ca7a47bdd0d58c897bb64ca8b1a2930827deebf82d0c718b50b32aefa1e2' 
  AND token = 'NFrH3fmk2fycz1VYEN+a67LDAiW5+aiIHWXN9EDG8Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}