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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24b46a3ae0372d245a34579d6c91f0ec64822d547d9a02aadba2138651b1f727' 
  AND token = 'DLoGneqG7czv2T20b4f1R6aQ//xCACZCwDssi1822Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}