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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a44d45d5b121d2f9c65ff4266cabdef6de9f89afdf52c5796165126a94718028' 
  AND token = 'vsM7kGXlS7fe+nd0dQb/xOo7kHQvh1RXVQhxPjrVnC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}