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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b2d0c62740d29be82f245aeebf41b5cb837da17f0c42021c69899edf5995a28' 
  AND token = 'DAZ8jLO+VFHWLlt66ncyz13SQYO9XOOZa4XxLw0lQj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}